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The medication enhances glucose-dependent insulin secretion, suppresses inappropriate glucagon release, delays gastric emptying, and reduces appetite through central mechanisms

Fat tissue Semaglutide also enhances energy expenditure

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The carbohydrate restriction of ketogenic diets further reduces glucose availability, potentially necessitating medication adjustments

The cell fluorescence results likewise confirmed that the GPX4 fluorescence intensity was attenuated after TPA stimulation compared with those in the control and TPA + TNF--treated groups (Fig