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For Bpc-157 specifically when targeting localized injuries, inject one to two inches from the injury site rather than directly into damaged tissue

A 2025 systematic review by Vasireddi and colleagues in HSS Journal screened 544 published papers and identified 36 meeting inclusion criteria 35 preclinical studies and only one human study: an uncontrolled, unblinded, retrospective case series of 12 patients receiving intra-articular BPC-157 for chronic knee pain, in which 7 of 12 (58%) reported self-described relief lasting more than 6 months, with no dose, effect size, or systematically collected adverse events published

doi:10.1007/978-1-4899-1471-2_45 Franekova V, Angin Y, Hoebers NT, Coumans WA, Simons PJ, Glatz JF,

most data are from plasma or peripheral cells (PBMCs)

doi: 10.1097/NRL.0b013e3181ebe59f