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Icariin has been demonstrated to directly induce ferroptosis in colorectal cancer cells while simultaneously promoting CD8 + T cell activation and IFN- secretion, thereby augmenting the therapeutic efficacy of programmed cell death protein1 (PD-1) checkpoint inhibitors (123)

Chronic alcohol consumption is the primary cause of thiamin deficiency in industrialized countries

The human tripeptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging

Glutathione is a naturally occurring antioxidant that is found in every cell of the body

Interestingly, the gut metabolic module aspartate degradation I, which converts L-aspartate to oxaloacetate by aspartate aminotransferase, was elevated in SAD patients and the authors hypothesized that bacterial aspartate aminotransferase enzyme activity may represent a link between gut microbiome function and the tryptophan-kynurenine pathway, a key physiological system in psychiatric disorders (Butler et al., 2023)