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doi:10.1023/A:1018955126402 Ionescu M, Frohman LA
Some people have the following side effects after a B6 IV therapy session: Loss of appetite Foul smells or tastes Headache Nausea Bruising Pain in the area or arm that had the injection Stomach pain Overdosing on vitamin B6 (when 500 mg or more are taken in a single day) Most of these side effects go away on their own within a short period of time
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Slightly more nerdy answer: because peptides are small, they can bind directly to cell receptors and trigger specific biological effects
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