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Jul 13 2002;151(2):43-6

We wanted to increase the likelihood that we were studying only patients who were being actively managed

Look for testing of some sort

25 In line with the role of ADAMTS-2 as an important procollagen type I N-endopeptidase, 9,12,17 we found abnormal processing of the N-propeptide of type I procollagen, with accumulation of pN1(I) and pN2(I) procollagen chains and near-absence of pC1(I) and pC2(I) procollagen chains in patients derived fibroblasts