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Before determining that a shortage is resolved, FDA considers a variety of factors, including the company's ability to meet current and historical demand, the amount in a manufacturers stock, affected market share, ability of alternate manufacturers to cover the demand, and confirmed market stabilization

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Considering this fact, a study developed dual dynamic-bond cross-linking between Fe, PA containing aldehyde groups and quaternized chitosan, (QCS) adhesive hydrogels dressing that could repeatedly close the wound to prevent infection and delay healing

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