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The participants were taking simvastatin, which can also lower blood pressure and may have overshadowed any effects of acetyl-L-carnitine [7][23]

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Exendin-4 has been shown to reduce advanced glycation end product (AGE)-induced interleukin (IL)-6 and TNF- production, the expression of receptor for AGE (RAGE), and cell death in mesangial cells (Wang et al., 2014)

Ozempic received FDA approval specifically for managing type 2 diabetes in adults, yet physicians legally prescribe it to patients without diabetes solely for weight reduction