GSH has the function of master antioxidant in all tissues and is involved in antioxidant defense, detoxication of xenobiotics, intracellular redox homeostasis, cysteine carrier/storage, cell signaling, protein folding and function, gene expression, cell differentiation/proliferation, immune response and antiviral defense, that make it a Samsonian (mighty) little molecule (1, 2)
Indirect markers include elevated oxidative stress markers, poor recovery from exercise, chronic fatigue, weakened immune function, or elevated liver enzymes
If it doesnt fit, we say so
SGLT2 inhibitors correct the abnormal activation of hypoxia-inducible factor-1 (HIF-1) (Wang YH
Future research directions are also discussed to advance our understanding and treatment of free radical-associated diseases