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Massachusetts saw a 255 percent surge in obesity-related GLP-1 prescriptions in 2024 one of the highest increases in the country while Point32Health reported a $382 million loss last year and has begun layoffs amid mounting costs

They are not established as identical to, or as safe and effective as, FDA-approved brand-name medication, and their availability is subject to changing FDA regulation in 2026

Dans ltude de phase 2 publie dans The Lancet chez des patients diabtiques, les troubles digestifs ont t dcrits comme gnralement lgers modrs , et plus frquents aux doses leves

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Health professionals themselves will be confused and looking to the guidance again, questioning their practice