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Past studies have reported that the protection was time- and dose-dependent and independent of competition for the adhesion sites

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HA is also a glycosaminoglycan, which means that it is a type of sugar molecule that has anti-inflammatory and antioxidant properties

Figure 4 6.3 Complementary endocrine actions: insulin sensitization, androgen modulation, and ovulatory regulation The clinical and molecular intersections of vitamin D, MI, and melatonin converge on three tightly connected endocrine domains central to the pathophysiology of PCOS: IR, androgen excess, and ovulatory dysfunction

Nature Reviews Cancer (2008) 9