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Het is deze afbraak van collageen en verminderde elasticiteit die veel van de hierboven genoemde fijne lijntjes veroorzaakt

Activated microglia proliferate and migrate to the lesion site, where they accumulate, with both beneficial and detrimental functions

But the speed and extent of reversal can vary from person to person

Selenium deficiency impaired bone and cartilage growth with the exhibition of premature chondrocyte hypertrophy as evidenced by an increased expression of COLX, compatible with the phenotypes in KBD cartilage 64