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doi: 10.1371/journal.pone.0083466 13 FoyerC

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The most commonly used approach is in vitro or ex vivo tests using diffusion cells, or more recently, the parallel artificial membrane permeability assay (Skin-PAMPA) and phospholipid vesicle-based permeation assay (PVPA) (Figure 4) [40], allowing for the quantification of the permeation of CACs through the skin

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