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A recent meta-analysis performed on patients with T2DM showed that all GLP-1 dose groups had a significantly higher incidence of vomiting compared to both placebo and conventional therapy, especially in individuals treated with exenatide [51]

doi:10.1080/07315724.2019.1661804 Kraemer WJ, Spiering BA, Volek JS, et al

Appetite & Metabolic Effects 3

doi: 10.1136/bmjmed-2023-000548

This relative insufficiency is one reason myo-inositol supplementation has become a standard adjunct in PCOS management guidelines in several countries and a frequent component of evidence-based fertility protocols under the headings Myo-Inositol for PCOS and Myo-Inositol for fertility support