glp 1 and multiple sclerosis Repurposing glucagon-like peptide-1 receptor agonists for the treatment of neurodegenerative disorders Frontiers | GLP-1 receptor agonists

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Ngo J, Choi DW, Stanley IA, Stiles L, Molina AJA, Chen PH, et al

However, excessive or sustained mitochondrial damage triggers pathological overactivation of mitophagy, contributing to cell death and tissue injury ( FIGURE 1 During AKI, dysfunctional mitochondria can induce the expression of peroxisome proliferator-activated receptor- coactivator 1 (PGC-1), which facilitates mitochondrial biogenesis and supports the maintenance of mitochondrial structure, function, and quantity

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