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Researchers observed that GHK-Cu influences expression of over 4,000 human genes based on microarray studies, with significant effects on genes involved in collagen synthesis, metalloproteinase regulation, antioxidant defense (SOD, glutathione), and growth factor signaling (TGF-, VEGF, FGF)

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b: n = 9) in vitro cultured with ( a ) 5%, 10%, or 20% SLE serum for 6, 16, 24 hours respectively, or with ( b ) 20 % HC, SLE or RA serum respectively for 16 hours

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