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Transcobalamin II receptor polymorphisms are associated with increased risk for neural tube defects

Another study using primary cortical neurons cultured from Pink1 -deficient mice revealed that FKBP5 can reduce Akt phosphorylation and promote MPP + -mediated neuronal death in the absence of Pink1 [91]

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Future trials are needed to compare the clinical and economic outcomes of capped glucarpidase doses across several institutions

MG is detoxified by the glyoxalase route by the sequential actions of GLYI and GLYII in a glutathione (GSH)-dependent manner, while GLYIII facilitates glutathione-independent detoxification under prolonged stress conditions