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It gives Retatrutide a different research profile from tirzepatide and has made it a key compound in studies involving metabolic signalling, appetite-related pathways, glucose response models, energy balance and cardiometabolic research

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Fat Loss & Metabolic Health Clinical research shows up to 24% body-weight reduction within 48 weeks in obese participants

The real differentiator may be the metabolic preservation effects seen with CagriSema in preclinical models, but human data confirming this advantage is still limited