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Without specific proof as to the exact cause of why a GLP-1 could cause a higher risk of developing NAION, we can hypothesize a bit and suggest hypovolemia and dehydration from perhaps weight loss, especially if the patient is getting a medication for hypertension and the weight loss has reduced the need for the hypertensive agent and thus the patient develops hypotension

Halawi, D.D

Side effects peaked at weeks 6-8 and resolved by week 12 for the majority

when the body has less available bile acid, it turns to LDL cholesterol as a replacement, effectively pulling LDL out of circulation and lowering it

In January 2024, the FDA clarified its position: peptides like research peptides and many others frequently marketed by peptide clinics are not approved for any use and cannot be legally compounded