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For example, mutations in the SETD2 gene, which encodes a methyltransferase responsible for H3K36me3, have been associated with ASD (case report) and neurodevelopmental disorders with or without macrocephaly overgrowth, highlighting the importance of this modification in brain development (Chen et al., 2021

Duzel A, Vlainic J, Antunovic M, Malekinusic D, Vrdoljak B, Samara M, et al

Another study found improvements in patients with serious heart conditions, including coronary heart disease and chronic heart failure

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