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Psychiatry 11, 561998
Simvastatin, also CYP3A4-dependent and more lipophilic, exhibits higher hepatotoxicity (25%) and greater DILI risk, making it less favorable in polypharmacy or liver disease [86]
Analysis of more recent pharmaceutical dispensing data show that in 2024, approximately 160,000 patients in New Zealand were dispensed a urate-lowering medicine, most often allopurinol (141 patients per 1,000 registered patients
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Using simple sterile water is an option for single-use applications, but for any protocol requiring multiple draws from the same vial, bacteriostatic water is the only acceptable choice
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