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This amplification of endogenous signaling rather than exogenous receptor activation is a mechanistically distinct approach to cognitive enhancement

Many nutrients have their action INSIDE the cell, which means that testing serum and blood levels just give us an indication of what may be available but that is assuming everything else is working properly: cellular activity, enzyme activity, receptor activity, etc

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When a person loses weight and the levels of circulating appetite-related hormones change, the hypothalamus adjusts parameters such as energy homeostasis, nutrient metabolism, and subjective appetite in response