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To that end, chemicals from the list generated herein are being selected and implemented in pre-validation studies of hPPAR and hPPAR transactivation assays ( Collectively this work will contribute to the development of the OECD TG NAM toolbox to assess the potential chemical hazards from obesogenic chemicals
Clambey, E
In the light of the current research, it is speculated that the maladaptive changes in the gut microbiota can influence the central nervous system and evoke depressive symptoms, and the development of depression can influence gut microbiome stability, and both of these hypotheses appear to be supported by the results of human and animal studies [100]
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