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Consistent with its more IGF1R-like behavior, we find that the L973F mutation in IR leads to decreased receptor internalization following insulin stimulation compared with WT-IR

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However, whereas the majority of hepatotoxic compounds cause centrilobular injury, some xenobiotics, such as allyl formage, elemental phosphorus, and allyl alcohol, preferentially damage periportal hepatocytes, presumably as a result of rapid first-pass uptake by these upstream hepatocytes

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If you see two packs with the same capacity, but one is significantly lighter and claims a higher C-rating, be cautious