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In sensitivity analysis, we used different analysis methods robust to pleiotropy and replicated using an l-carnitine isoform, acetyl-carnitine

To elucidate the transcriptional program associated with GLA-mutant kidney organoids and the consequences, 100 differentially expressed genes (DEGs) were first identified on the basis of fold change values (50 genes were upregulated and downregulated in GLA-mutant Fabry kidney organoids compared with WT kidney organoids

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