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We propose that curcumin exerts its broad therapeutic effects via a unified inflammationoxidative stress axis, primarily by inhibiting NF-B and NLRP3 activation, reducing ROS and pro-inflammatory cytokines (TNF-, IL-1/18), as seen across models of depression, metabolic disorders, and neurodegeneration

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N-acetyl cysteine (NAC) is the current standard of care for APAP overdose 12 , which is It is believed to have benefit in APAP hepatotoxicity by increasing the availability of the glutathione precursor cysteine, thereby driving glutathione synthesis

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Vyshnava SS, Pandluru G, Kanderi DK et al (2020) Gram scale synthesis of QD 450 coreshell quantum dots for cellular imaging and sorting