PMID 15331224
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A compound isolated from the reptiles saliva was found to bind to human GLP-1 receptors, with the added perk that it was slow to break down in the body
Its possible that any benefits we see with GLP-1s on cancer risk will be enhanced by newer-generation medications.
Abbreviations H 2 O 2 : Hydrogen peroxide MTT: 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide LDH: Lactate dehydrogenase ROS: Reactive oxygen species SOD: Superoxide dismutase CAT: Catalase MDA: Malondialdehyde PPAR: Peroxisome proliferator-activated receptor CPT1: Carnitine palmitoyl transferase 1 ACOX: Acyl-CoA oxidase DPPH: 1,1-diphenyl-2-picryl-hydrazyl DCFH-DA: 2,7-dichlorofluorescein diacetate DMSO: Dimethyl sulfoxide