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When applied to the skin, it may also cause mild skin or eye irritation ( Additionally, there is concern over mixing MSM with alcohol since other sulfur-containing medications can cause adverse reactions when mixed with alcoholic beverages ( However, no studies have explored this potentially problematic combination yet

supplementation is hypothesized to mitigate oxidative damage in the central nervous system

While short-term usage appears safe for most people, more research is needed to understand the potential effects of prolonged use fully

Note: These higher doses are typically used for specific periods and should be discussed with a healthcare professional, especially if you plan to stay at that level for more than a few months