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3.3 Ruthenium compounds Cisplatin and other platinum(II)-based antitumor drugs are widely recognised for the treatment of various types of cancer, primarily ovarian, testicular, and lung cancer

8 Moreover, changes in systemic energy metabolism may impair the energetic support necessary for skeletal homeostasis and influence bone-active hormonal pathways

doi: 10.1038/gt.2012.81 183 TraisterRSFabreSWangZXiaoXHirschR

Increased pituitary GH raises IGFI, which then affects the gonadal axis

Research shows that patients who stop GLP-1 therapy regain 5080% of lost weight within 612 months if lifestyle habits don't anchor the loss