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The metabolic benefits of weight loss typically outweigh any lingering medication effects

Thank you to our sponsors AG1 (Athletic Greens): InsideTracker: Thesis: Supplements from Momentous For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Introduction (00:05:50) Hormone Optimization (00:07:00) Salutogenesis: A Powerful Way to Conceptualize Health (00:10:03) Estrogen and Testosterone: Sources, Levels and Ratios (00:15:46) The Power of Competition, Plus: Anxiety, Persistence and Dopamine (00:20:58) Testosterone and Libido Pre-Ovulation (00:21:48) Estrogen and Sexual Receptivity

Adverse effect management : Educate patients about expected gastrointestinal effects and when to seek medical attention

This is the smallest adjustment you can make and carries virtually no additional risk

Underdosing due to tablet splitting or improper administration may result in subtherapeutic drug levels, leading to inadequate HbA1c reduction in patients with diabetes or insufficient weight loss in those using the medication for obesity management