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This is consistent with B12 role in energy metabolism and with the depletion pattern described above

This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive

Normal serum B12 ranges vary between laboratories, so results should be interpreted using your local laboratory's reference ranges

However, the FDA repeatedly stated it "cannot determine the adequacy" of many responses or found them "not adequate." Regulatory consequences FDA warned that "failure to adequately address this matter may result in regulatory action being initiated by the FDA without further notice

Immunity 52 , 668682.e667 (2020)