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In the cell-free GCLC enzymatic assay, BSO inhibited the activity of GCLC with an IC50 of 570 nM [95% confidence interval (CI) 429757 nM

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GLP-1 Synthesis GLP-1 and GLP-2 were identified in the distal small intestinal mucosa as the product of post-translational processing by prohormone convertase 1/3 (PC1/3) of the proglucagon gene product (9) which in the Islets is processed by PC2 to yield glucagon (75, 87, 97)

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This observation indicates that dietary PUFA exposure impacts the course of CD