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Intolerable side effects such as persistent nausea, vomiting, diarrhea, or fatigue top the list of common reasons why people may stop, Salamon says

This can look like: Feeling hungry sooner after meals Cravings appear more often, especially in the evening Food noise feels louder than before This shift is expected as your body returns to controlling appetite without the extra support from the injection

Short-chain fatty acids stimulate the release of gut hormones via the G-protein-coupled receptor FFAR2

"Weight loss is a side effect for both medicines, but Ozempic has a bigger effect," Ponder says

What are GLP-1 medications