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These cells recognize molecular patterns of gut microbiota via pattern-recognition receptors (PRRs), such as lipopolysaccharides (LPS) and peptidoglycans, initiating immune responses (Takeuchi and Akira, 2010)

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Five-year follow-up data presented at the AAOS 2026 meeting indicated that GLP-1 users had a significantly higher risk of osteoporosis than matched controls (4.1% to 3.2%)