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Key findings Patients mean age at initiation was 55.1 (13.3) years, 65.2% were female, 73.7% were white, and 61.3% had T2D

This allows assessment of the amylin analog effects and GI tolerance before escalating to higher research doses

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It notes some evidence points to lower-dose maintenance after initial weight loss as a way to reduce rebound with fewer side effects, while other clinicians favor intermittent schedules or switching therapies