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Why the pairing is plausible The logic for combining them comes from pathway biology: tesamorelin works through the GHRH receptor, while ipamorelin works through the ghrelin/GHS-R1a receptor

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Enhanced thermogenesis would increase total daily energy expenditure, creating a more favorable energy balance for fat loss

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High NNMT activity has also been linked to: Poor mitochondrial function Increased oxidative stress Accelerated fat storage Inhibiting this enzyme helps reverse those metabolic imbalances