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For example in human gastrointestinal cell lines, in the case of MKN45 cells, the enzyme in a range of concentration from 100 to 600 g/mL but non-dose dependently reduced cell survival at 72h of treatment (81)

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That being said, current research has been focused on the ability of the peptide to reduce body weight as well as the identifying the optimal dose-response relationship between treatment with cagrilintide and overall body weight [1]

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