side effects of discontinuing semaglutide What happens when you stop weight-loss drugs like GLP-1 injections? The answer is not as simple as “you gain it all back.” A study published in Diabetes, Obesity and Metabolism analysed 7,938 How to Not Gain Weight

As a result, people may be more likely to stick with the medication and experience successful weight loss

The gradual dose titration protocols for both formulations aim to minimize gastrointestinal side effects

Symptoms often resolve within 6 to 16 weeks after they startsometimes on their own, and sometimes after adjusting the medication

Again, much of this is water and reduced food volume in the GI tract, not pure fat loss

Similar patterns have been observed with liraglutide in the SCALE trials and tirzepatide in the SURMOUNT-4 study, suggesting this is a consistent finding across multiple incretin-based anti-obesity agents