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My summer in the Jander lab gave me insight into what it would be like to perform research full-time

Insulin resistance plays an important role in the pathophysiology of comorbid T2DM and depression and can be a trigger for dysregulation of insulin- and GLP-1-mediated signaling (both central and peripheral), neuroendocrine disorders (hypothalamicpituitaryadrenal system dysfunction and monoaminergic neurotransmission disorders), chronic low-intensity inflammation, oxidative stress, and disorders of the microbiota-gut-brain system, reducing the level of neurotrophic factors in the brain and changing synaptic plasticity

Start with protein-rich meals, add fiber-containing foods you tolerate, include fluids, and choose smaller meals if large portions cause nausea or fullness

Certain red flag features indicate the need for urgent or emergency assessment, and patients should be educated about these warning signs

Aim for at least 64 ounces of water daily, more if you exercise regularly