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More important than how much weight is lost, Drucker told CNN Friday, are the health benefits GLP-1 medicines have shown in studies, which include reduction of metabolic liver disease and sleep apnea and osteoarthritis and heart disease and strokes, which dont appear to be strictly weight-loss dependent. Even if next-generation medicines show greater degrees of weight loss, Drucker said, it takes several years for trials to prove benefits on other outcomes like those, which may be more meaningful to patients and doctors