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PPIs were not directly tested in these interaction studies

Food intake data were collected on a continuous basis from 24 h before dosing (allowing for replenishment of food as well as dosing time) and throughout the study

Health Improvement: Weight loss achieved with the support of phentermine can lead to better management of weight-related conditions such as high blood pressure, type 2 diabetes, and high cholesterol

Breathing Aid: By lubricating nasal passages, mucus facilitates easier breathing

Results for the full list of phenotypes for STEP 1 and STEP 2 are shown in Supplementary Tables 9 and 10 (hallmark analyses) and Supplementary Tables 11 and 12 (deCODE analyses), including q values