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Since chronic hyperglycemia imposes deleterious effects on -cell function by building up glucose toxicity [26], ameliorating glucose toxicity with intensive insulin therapy may restore -cell function [27,28] and improve -cell incretin sensitivity through a similar mechanism

Men who have used tirzepatide report dramatic body composition changes that often exceed the averages reported in mixed-gender clinical trials

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"These past couple of weeks I have been dizzy on and off sometimes really bad." u/WeekByWeek Dose increases are a common trigger: "I started getting dizzy when I went to the 1.0mg dose." u/DoseDidIt Responses vary widely between individuals