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Research published in the European Journal of Endocrinology shows that ipamorelin released growth hormone from primary rat pituitary cells with potency and efficacy similar to GHRP-6, with EC50 values of 1.30.4 nmol/L and maximum efficacy of 855%

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Moreover, hippocampal neurogenesis reduces neuronal damage by replacing lost neurons, which appears to improve depressive-like behavior (Zhang et al., 2008)

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These factors impacted the health state utility of the induvial over time