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Excessive MDA in liver tissue will consume a large amount of antioxidative factors, such as SOD and GSH, which can protect liver from the attacks of free radicals, but once the balance is broken, SOD and GSH will be unable to protect liver against the excessively increased MDA (22,23)

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Elucidation of how clofazimine treatment may balance the regulation of innate and adaptive immune responses will be important to understanding its potential clinical efficacy