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Fifty units of (Speywood) botulinum toxin type A (Dysport) were subcutaneously injected in eight points distributed mostly along V2 in the lateral periorbital area and in three injection points in the inferolateral area taking care not to infiltrate too much directly under the eye to minimise potential aesthetic side effects

Structure of a yeast catalytic step I spliceosome at 3.4 A resolution

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