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A separate ASD cohort from China also revealed fewer butyrate-producing bacteria, including Faecalibacterium and Coproccus , among ASD patients and disrupted SCFA metabolism and neurotoxin degradation pathways, which were suggested to be ASD biomarkers [306]
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Metformin has also been reported to prevent human pancreatic islets from impairment of glucose-stimulated insulin secretion induced by high glucose in human pancreatic islets 17
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