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The effects were modest and the clinical relevance uncertain, but they highlight that GHS-R1a signaling extends beyond the somatotroph axis and has the potential to influence multiple endocrine systems

The STEP 1 clinical trial, published in the New England Journal of Medicine , found that once-weekly semaglutide produced an average body weight reduction of 14.9% over 68 weeks

Whittaker MM, Barynin VV, Antonyuk SV, Whittaker JW

Social behavior was evaluated using three-chamber testing

At Vital Health Medical Care, each patient receives a customized exercise plan developed in collaboration with fitness experts, tailored to their current fitness level, physical capabilities, and personal goals