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She also recommends starting a fiber supplement at the same time with a GLP-1 to prevent constipation

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Pool of Seven Controlled Clinical Trials Adverse reactions were also evaluated in a larger pool of adult patients with type 2 diabetes mellitus participating in seven controlled clinical trials which included two placebo-controlled trials (SURPASS-1 and -5), three trials of MOUNJARO in combination with metformin, sulfonylureas, and/or SGLT2 Inhibitors (SURPASS-2, -3, -4) [see Clinical Studies (14.3)] and two additional trials conducted in Japan

For patients who respond well to semaglutide, the lower cost makes it an attractive choice

Many people are concerned about feeling tired