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Magnesium blocks N -methyl-d-aspartate (NMDA) receptors in a voltage-dependent manner, preventing the development of central sensitization
It may be reasonable to focus on whether the combination of GLP-1RAs and SGLT2is, which are expected to have complementary effects based on large-scale clinical trial results, can further reduce cardiovascular and renal events in patients with diabetes
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Integrating advanced imaging techniques and biomarkers could also help monitor therapeutic outcomes
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