For Real-Time PCR amplification, the Maxima SYBR Green qPCR Master Mix was used, with primers designed for the target genes StAR (Steroidogenic Acute Regulatory Protein), 3-HSD (3-Hydroxysteroid Dehydrogenase), Cyp17a (Cytochrome P450 17A1), Aromatase and GAPDH as an internal control
Auch die metabolische Kontrolle und die kardiovaskulren Risikofaktoren verbesserten sich, trotzdem konnten die kardiovaskulren Ereignisse nicht signifikant reduziert werden (2)
Following dichotomization of ALT responders based on a median 12.9% decrease from baseline, we found that ALT responders were younger in age and did not have severe diabetes compared with ALT non-responders
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