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More serious reactions can include pancreatitis, gallbladder problems, kidney injury, thyroid tumors, severe allergic reactions, vision changes, and low blood sugar

Your prescriber will usually reduce the sulfonylurea or insulin dose when initiating GLP-1 therapy

While both medications can contribute to weight loss individually, using them together may provide additional advantages: Ozempic (semaglutide) works by mimicking a hormone called GLP-1, which helps regulate appetite and food intake

She adds that starting with a lower dose of 2 mg/week instead of 4 mg/week may help mitigate adverse effects

Heart, Kidney, and Blood Sugar: Where the Record Lives Semaglutides cardiovascular, kidney, blood-sugar, and weight evidence is attached to different doses and populations